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Dr. Alexandra LaStella, PharmD, RPh

     alexandra.lastella14@gmail.com

     0009-0006-4479-9915


Dr. Katherine Gabriel, PharmD, RPh

     kathyg0521@gmail.com

     0009-0004-0341-9744

LaStella A, Gabriel K. Integrative Cardiovascular Pharmacology: Evaluating the Role of Taurine in Blood Pressure Regulation and Vascular Health. J Scrip Pharm. Published online July 31, 2025. doi: 10.70390/9gz0z9lsm

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Integrative Cardiovascular Pharmacology: Evaluating the Role of Taurine in Blood Pressure Regulation and Vascular Health

Abstract

DOI: 10.70390/9g0z9lsm

Taurine, a naturally occurring sulfur-containing amino acid, has gained attention for its potential to lower blood pressure and improve vascular health. Through multiple biological actions, such as regulating ion channels, enhancing antioxidant defenses, and modulating autonomic nervous system activity, taurine supports blood vessel function and reduces vascular stiffness. Evidence from randomized controlled trials and meta-analyses consistently shows that taurine supplementation, particularly at doses of 1.5 to 6 grams per day, leads to significant reductions in systolic and diastolic blood pressure, with the strongest effects observed in hypertensive and metabolically at-risk populations. Importantly, taurine is well tolerated with minimal adverse effects reported. This literature review synthesizes the current mechanistic and clinical evidence to evaluate taurine’s role as a safe and effective adjunct therapy for managing elevated blood pressure and improving cardiovascular outcomes.

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